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1) Why Do the Two DNA Strands Need to Be Going in the Opposite Directions? (2-3 Sentences) Hint: Think About Base Pairing.

Question

1) Why do the two DNA strands need to be going in the opposite directions? (2-3 sentences) Hint: think about base pairing.

Solution

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Answer

DNA strands run antiparallel to allow for proper base pairing. Adenine (A) must pair with thymine (T), and guanine (G) must pair with cytosine (C); this complementary pairing is only possible with antiparallel orientation due to the molecules' shapes and hydrogen bonding locations.