Slide 12 G1 phase, mitosis, S phase, metaphase , telophase, G2 phase, anaphase, prophase Chapter 10 : Cell Growth and Divisi 2. Cell division (2) -Events of the cell cycle: -Interphase:- __ : growth cell and normal metabolism. __ : DNA replication. __ : organelles are replicated. -M phase: __ : __ : longest phase of mitosis.migration of centrioles to opposite poles;formation of the spindle:chromosomes coil more tightly; nucleosome disappears; nuclear membrane disintegrates. __ : chromosomes line up across the center of the cell; microtubules connect chromosome to opposite poles. __ : sister chromatids split becoming chromosomes; these new chromosomes migrate towards the opposite poles. __ : chromosomes decondense nucleosome reappears; nuclear membrane re-forms. __ : cells split into two daughter cells with the same genetic material cleavage furrow (animal cells) or cell plate (plant cells)

**Slide 12**<br />**G1 phase, mitosis, S phase, metaphase, telophase, G2 phase, anaphase, prophase**<br />**Chapter 10: Cell Growth and Division**<br />**2. Cell division (2)**<br />**- Events of the cell cycle:**<br /><br />* **Interphase:**<br /> * **G1 phase:** cell growth and normal metabolism.<br /> * **S phase:** DNA replication.<br /> * **G2 phase:** organelles are replicated.<br /><br />* **M phase (Mitosis):**<br /> * **Prophase:** longest phase of mitosis. Migration of centrioles to opposite poles; formation of the spindle; chromosomes coil more tightly; nucleolus disappears; nuclear membrane disintegrates.<br /> * **Metaphase:** chromosomes line up across the center of the cell (metaphase plate); microtubules connect centromeres of chromosomes to opposite poles.<br /> * **Anaphase:** sister chromatids separate, becoming individual chromosomes; these new chromosomes migrate towards the opposite poles.<br /> * **Telophase:** chromosomes decondense; nucleoli reappear; nuclear membrane re-forms around each set of chromosomes.<br /><br />* **Cytokinesis:** cells split into two daughter cells with the same genetic material. Cleavage furrow (animal cells) or cell plate (plant cells) forms. (Note: Cytokinesis is sometimes considered a separate phase, not part of mitosis itself, but it is a crucial part of the cell division process.)<br />