12. Choose a response from the key below to name the hormone(s)produced by the cell types listed. Key: A. calcitonin d. glucocorticoids g. PTH b. GH, prolactin C. insulin T_(4)/T_(3) C. glucagon f. mineralocorticoids 1. TSH, ACTH, FSH, LH __ 7. zona glomerulosa cells __ 1. parafollicular cells of the thyroid __ 2. follicular cells of the thyroid __ 3. beta cells of the pancreatic islets __ 4. alpha cells of the pancreatic islets __ 5. basophil cells of the anterior pituitary __ 6. zona fasciculata cells __ 8. parathyroid cells __ 9. acidophil cells of the anterior pituitary axcess amounts of growth hormone Describe the signs and symptoms that these tumors

* **7. zona glomerulosa cells:** **f. mineralocorticoids** (primarily aldosterone)<br />* **1. parafollicular cells of the thyroid:** **A. calcitonin**<br />* **2. follicular cells of the thyroid:** **e. T₄/T₃** (thyroxine and triiodothyronine)<br />* **3. beta cells of the pancreatic islets:** **c. insulin**<br />* **4. alpha cells of the pancreatic islets:** **e. glucagon**<br />* **5. basophil cells of the anterior pituitary:** **i. TSH, ACTH, FSH, LH** (thyroid-stimulating hormone, adrenocorticotropic hormone, follicle-stimulating hormone, luteinizing hormone)<br />* **6. zona fasciculata cells:** **d. glucocorticoids** (primarily cortisol)<br />* **8. parathyroid cells:** **g. PTH** (parathyroid hormone)<br />* **9. acidophil cells of the anterior pituitary:** **b. GH, prolactin** (growth hormone and prolactin)<br /><br /><br />**Excess Growth Hormone and Associated Tumors:**<br /><br />Tumors in the anterior pituitary can lead to excess growth hormone (GH) secretion. The resulting signs and symptoms depend on the age of onset:<br /><br />* **Gigantism:** Occurs in children before the closure of the epiphyseal plates (growth plates). Excessive GH leads to abnormally rapid growth in height, as well as enlarged hands and feet. Internal organs may also be enlarged.<br /><br />* **Acromegaly:** Occurs in adults after the epiphyseal plates have closed. Because bones can no longer lengthen, the excess GH causes bones to thicken and enlarge, particularly in the face, hands, and feet. Common features include a prominent jaw (prognathism), enlarged brow ridge, enlarged hands and feet, and coarsening of facial features. Soft tissues also grow, leading to enlarged lips, tongue, and nose. Internal organs may also enlarge (organomegaly). Other symptoms can include joint pain, carpal tunnel syndrome, excessive sweating, headaches, and vision problems.<br />