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Human blood type is controlled by three different alleles: P, P,and i. The F^A and P^B are codominant, while the i allele is recessive. A man with blood type A has a son with blood type B and a daughter with blood type AB. What are all the possible genotypes of the biological mother?

Question

Human blood type is controlled by three different alleles: P, P,and i. The F^A and P^B are codominant, while the i allele is recessive. A man with blood type A has a son with blood type B and a daughter with blood type AB. What are all the possible genotypes of the biological mother?

Human blood type is controlled by three different alleles: P, P,and i. The F^A and P^B are codominant, while the
i allele is recessive. A man with blood type A has a son with blood type B and a daughter with blood type
AB. What are all the possible genotypes of the biological mother?

Solution

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SashaProfessional · Tutor for 6 years

Answer

To determine the possible genotypes of the biological mother, we need to consider the blood types and the inheritance patterns of the alleles involved.<br /><br />The man has blood type \( A \), which means his genotype could be either \( I^{A}I^{A} \) or \( I^{A}i \).<br /><br />The son has blood type \( B \), which means his genotype must be \( I^{B}i \). Since the father cannot provide an \( I^{B} \) allele, the mother must have provided the \( I^{B} \) allele.<br /><br />The daughter has blood type \( AB \), which means her genotype is \( I^{A}I^{B} \). The father can provide the \( I^{A} \) allele, so the mother must have provided the \( I^{B} \) allele.<br /><br />Given these conditions, the mother must have at least one \( I^{B} \) allele. Therefore, the possible genotypes for the mother are:<br /><br />1. \( I^{B}I^{B} \)<br />2. \( I^{B}i \)<br />3. \( I^{A}I^{B} \)<br /><br />These genotypes would allow the mother to pass on the necessary alleles to produce a son with blood type \( B \) and a daughter with blood type \( AB \).
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